Opportunity Information: Apply for HT942526ERPRPA

The DoD Epilepsy Research Program (ERP) Research Partnership Award is a discretionary federal grant opportunity administered through the Defense Health Agency Contracting Activity (DHACA). Its central purpose is to fund collaborative research teams that can tackle high-priority questions in post-traumatic epilepsy (PTE) in a way that a single lab or investigator could not realistically accomplish alone. The program is explicitly oriented toward work that matters to people living with PTE, as well as their families and care partners, and it emphasizes research approaches where different investigators bring genuinely distinct and complementary expertise to solve a shared, central problem in the field.

A defining feature of this award is the required partnership structure. Each proposed project must involve at least two principal investigators working together under one overarching study, with roles divided into clearly defined parts that fit together into a unified research plan. The mechanism is designed to reward synergy: the expectation is not merely parallel projects under one umbrella, but a coordinated effort where the combined perspectives, methods, datasets, or clinical and translational capabilities produce outcomes that would be difficult or impossible if each investigator pursued the question independently.

The application process is organized around an initiating-versus-partnering model. Only the Initiating Principal Investigator submits the pre-application, which functions as the entry point for the team. However, if invited to the next stage, all participating PIs must submit full applications. The Partnering PI or PIs do not submit identical full packages; instead, they submit an abbreviated application focused specifically on their distinct portion of the overall project. If the proposal is selected for funding, the structure carries through into the award itself: each PI is issued a separate award made to their recipient organization, reflecting the distributed, multi-institution nature that many partnerships require.

The opportunity also carries an important coordination risk that teams need to plan for. Because the applications are linked as a single research project across multiple submissions, the entire set of associated applications may be withdrawn from consideration if either the initiating application or any partnering application is rejected or administratively withdrawn. Practically, this means the partnership must be tightly managed from the start, with strong alignment on compliance, submission readiness, and administrative requirements across all participating institutions, since one weak link can jeopardize the full project.

A notable new restriction applies for FY26: an investigator may be listed as a PI on only one FY26 ERP Research Partnership Award application. This limits how widely a single investigator can participate as a PI across multiple competing teams in the same cycle, and it encourages applicants to choose partnerships strategically rather than spreading effort across multiple submissions.

From the published opportunity details, the funding opportunity number is HT942526ERPRPA, and the activity category is Science and Technology and other Research and Development under CFDA 12.420. Eligibility is listed as unrestricted, indicating a broad applicant pool rather than a narrow set of institution types. The opportunity’s original closing date is August 17, 2026, and the government anticipates making one award under this announcement. The award ceiling is not specified in the provided source data, so applicants would need to consult the full notice or program announcement for budget limits, period of performance, and any cost-sharing or allowability rules.

  • The Defense Health Agency Contracting Activity - DHACA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoW Epilepsy Research Partnership Award" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420.
  • This funding opportunity was created on 2026-05-21.
  • Applicants must submit their applications by 2026-08-17. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: Unrestricted.
Apply for HT942526ERPRPA

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FAQs: DoD Epilepsy Research Program (ERP) Research Partnership Award

What is the DoD ERP Research Partnership Award?

The DoD Epilepsy Research Program (ERP) Research Partnership Award is a discretionary federal grant opportunity administered through the Defense Health Agency Contracting Activity (DHACA). It is designed to fund collaborative research teams addressing high-priority questions in post-traumatic epilepsy (PTE).

What is the main purpose of this funding opportunity?

The central purpose is to support coordinated, multi-investigator research efforts that can solve PTE problems that a single lab or investigator could not realistically accomplish alone. The award is intended to promote synergy across distinct and complementary expertise within one unified project.

What research area is the program focused on?

This opportunity is focused on post-traumatic epilepsy (PTE), including research questions considered high priority in that field.

Who is the intended beneficiary of the research?

The program emphasizes work that matters to people living with PTE, as well as their families and care partners. Proposed research should be oriented toward outcomes and insights that are meaningful for these communities.

What is the required partnership structure for an application?

Each project must include at least two principal investigators (PIs) collaborating under a single overarching study. The investigators must have clearly defined roles that combine into a unified research plan.

Does the award support separate projects bundled together, or a single coordinated project?

The mechanism is designed to reward synergy. It is not intended for parallel, loosely connected projects. Instead, it expects a coordinated effort where the combination of methods, datasets, clinical or translational capabilities, and perspectives leads to outcomes that would be difficult or impossible for the investigators to achieve independently.

How is the application process organized across multiple PIs?

The application process follows an initiating-versus-partnering model. Only the Initiating PI submits the pre-application. If the team is invited to the next stage, all participating PIs submit full applications.

Who submits the pre-application?

Only the Initiating Principal Investigator submits the pre-application, which serves as the entry point for the team.

Do Partnering PIs submit full applications?

Yes, if invited to the next stage, all participating PIs must submit full applications. However, Partnering PI(s) submit an abbreviated application focused on their distinct portion of the overall project rather than an identical full package.

How many awards does the government anticipate making under this announcement?

Based on the provided opportunity details, the government anticipates making one award under this announcement.

What happens if one partner application is rejected or withdrawn?

Because the applications are linked as a single research project across multiple submissions, the entire set of associated applications may be withdrawn from consideration if either the initiating application or any partnering application is rejected or administratively withdrawn.

What does the linked-application risk mean for teams in practice?

It means teams should plan for tight coordination across all participating institutions, including compliance, submission readiness, and administrative requirements. A weakness in any one linked submission can jeopardize the full project.

How are awards issued if the project is selected for funding?

If selected, each PI is issued a separate award made to their recipient organization. This reflects the distributed, multi-institution structure that many partnerships require.

Is there a limit on how many applications an investigator can join as a PI for FY26?

Yes. For FY26, an investigator may be listed as a PI on only one FY26 ERP Research Partnership Award application.

What is the funding opportunity number?

The funding opportunity number is HT942526ERPRPA.

What is the activity category and CFDA listing?

The activity category is Science and Technology and other Research and Development, under CFDA 12.420.

Who is eligible to apply?

Eligibility is listed as unrestricted, indicating a broad applicant pool rather than a narrow set of institution types.

What is the closing date for this opportunity?

The original closing date is August 17, 2026.

Is the award ceiling or maximum budget specified in the information provided?

No. The award ceiling is not specified in the provided source data. Applicants would need to consult the full notice or program announcement for budget limits.

Are the period of performance, cost-sharing requirements, or detailed cost allowability rules provided here?

No. The provided information indicates that applicants should consult the full notice or program announcement for the period of performance and any cost-sharing or allowability rules.

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