Opportunity Information: Apply for CDC RFA PS20 20040401SUPP23
The National Network of Sexually Transmitted Diseases Clinical Prevention Training Centers (NNPTC) Program Supplement is a CDC cooperative agreement funding opportunity (CDC RFA PS20-20040401SUPP23; CFDA 93.978) intended to strengthen the US response to the mpox outbreak by expanding training and technical assistance capacity within the existing NNPTC network. Mpox is described as a zoonotic orthopoxvirus infection historically endemic in parts of Central and West Africa, with a notable surge in cases beginning in mid-May 2022 in the United States and other countries that previously had limited mpox activity. While mpox can affect anyone through close contact, the opportunity emphasizes that the current outbreak has disproportionately affected gay, bisexual, and other men who have sex with men (MSM), largely due to transmission patterns involving sustained skin-to-skin contact, including sexual contact, and exposure to contaminated items such as shared linens. Because mpox can resemble other sexually transmitted infections (STIs) clinically (for example, conditions that cause genital lesions or proctitis) and because co-infections with STIs are common, the supplement frames mpox as closely aligned with sexual health services and, in many settings, as being managed similarly to STIs.
The supplement leverages the NNPTC network because these centers already focus on sexual and reproductive health training for clinicians and public health professionals, have established expertise in infections spread through sexual contact, frequently serve MSM-focused clinical and public health audiences, and have nationwide geographic reach through partnerships with health departments and universities. The overall goal is to use those strengths to help clinicians and clinical systems integrate mpox prevention and care into routine sexual health care, rather than treating mpox as a separate, stand-alone effort. The approach is explicitly described as syndemic, meaning it aims to address mpox in the real-world context where overlapping epidemics and co-occurring conditions (including STIs and other health inequities) interact and compound risk and burden, particularly in affected communities.
Programmatically, this is a non-competitive supplemental NOFO that funds components A, B, and C under the broader PS20-2004 NNPTC award structure, meaning it is designed to add targeted mpox-related work on top of an existing NNPTC framework. Recipients are expected to develop an implementation strategy and then deliver training and technical assistance to healthcare providers and clinical settings. The training and support are meant to cover the practical and clinical essentials needed for frontline integration: mpox epidemiology and transmission; recognition of clinical presentation and differentiation from similar STI presentations; diagnostic testing; treatment considerations (noting there is no mpox-specific treatment, but that smallpox-related countermeasures may be used because of viral relatedness); vaccination strategy and delivery, including both post-exposure prophylaxis (PEP) and pre-exposure prophylaxis (PrEP); and prevention approaches appropriate for sexual health settings.
Administratively, the opportunity is run by the US Department of Health and Human Services, Centers for Disease Control and Prevention (CDC), within NCHHSTP. It is a discretionary cooperative agreement, which typically signals substantial CDC involvement in project direction, coordination, and technical collaboration. Eligibility is listed as unrestricted, subject to any additional clarifications in the full notice. The application closing date noted is April 13, 2023 (with electronic submission due by 11:59 pm ET). The award ceiling is $800,000, with an expected eight awards. In short, the supplement funds NNPTC-led, nationwide clinician training and on-the-ground technical assistance so mpox vaccination, diagnosis, and clinical management can be built into everyday sexual health care workflows, with particular attention to the populations and clinical presentations most affected in the current outbreak.Apply for CDC RFA PS20 20040401SUPP23
- The Department of Health and Human Services, Centers for Disease Control - NCHHSTP in the health sector is offering a public funding opportunity titled "The National Network of Sexually Transmitted Diseases Clinical Prevention Training Centers (NNPTC) Program Supplement" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.978.
- This funding opportunity was created on Mar 14, 2023.
- Applicants must submit their applications by Apr 13, 2023 Electronically submitted applications must be submitted no later than 1159 pm ET on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $800,000.00 in funding.
- The number of recipients for this funding is limited to 8 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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