Opportunity Information: Apply for PAR 18 599
The Shared Instrumentation for Animal Research (SIFAR) Grant Program (PAR-18-599) is an NIH funding opportunity designed to help groups of NIH-funded investigators obtain the advanced instrumentation they need to conduct animal-based experiments across the full range of NIH-supported biomedical research. The core idea is shared access: rather than funding equipment for a single lab, SIFAR supports equipment that will be jointly used by multiple investigators whose NIH-funded projects require the same kinds of animal research capabilities. The program covers both purchases of new equipment and upgrades of existing equipment, as long as the requested instruments are necessary to carry out research using animals or closely related animal-derived materials.
A defining feature of this opportunity is that it supports clusters of instruments, not single standalone purchases. Applicants are expected to propose either a specialized, integrated system made up of multiple commercially available components or a coordinated set of instruments that together enable a focused, well-defined thematic area of animal research. NIH indicates a preference for uniquely configured systems, particularly where the configuration enables innovative approaches or potentially transformative investigations. In practice, this means applications are strongest when they clearly explain why the instruments must be assembled or configured as a group, how the combined system improves capability beyond what is already available, and how the shared resource will accelerate or expand the science of the participating NIH-funded users.
The FOA is broad with respect to species and research domains. It supports state-of-the-art commercially available technologies used in research with any vertebrate or invertebrate animal species. That breadth is meant to accommodate many kinds of instrumentation commonly required for animal experiments, including systems that improve measurement, monitoring, imaging, phenotyping, behavioral assessment, or other specialized animal research workflows, provided the request aligns with active NIH-funded research needs and will be operated as a shared resource.
There are specific budget and pricing rules that shape what can be requested. At least one item within the proposed instrumentation cluster must have a cost of at least $50,000 after all applicable discounts. At the same time, no instrument included in the cluster may cost less than $20,000 after all applicable discounts, which effectively prevents applicants from bundling numerous small accessories or low-cost items to create an artificial cluster. While there is no stated maximum price for an individual instrument, the overall award ceiling is $750,000. The announcement also notes that this is an S10 mechanism and that clinical trials are not allowed under this FOA.
Eligibility is oriented toward research-performing organizations that can manage shared instrumentation and support multiple NIH-funded users. Eligible applicants include public and state-controlled institutions of higher education, private institutions of higher education, and nonprofit organizations (both 501(c)(3) and non-501(c)(3)) other than institutions of higher education, along with other applicants as described in the FOA’s additional eligibility information. The sponsoring agency is the Department of Health and Human Services, National Institutes of Health, and the activity falls under the health category (CFDA 93.351). For the cycle reflected in the provided data, the original closing date was May 31, 2018, with an expected 12 awards and a maximum award amount of $750,000.
Overall, SIFAR is best understood as a targeted NIH shared-instrumentation program for animal research that emphasizes collaborative use, modern commercially available technologies, and thoughtfully designed multi-instrument configurations that meaningfully expand what NIH-funded investigators can do in animal-based biomedical science.Apply for PAR 18 599
- The Department of Health and Human Services, National Institutes of Health in the health sector is offering a public funding opportunity titled "Shared Instrumentation for Animal Research (SIFAR) Grant Program (S10 Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.351.
- This funding opportunity was created on Jan 29, 2018.
- Applicants must submit their applications by May 31, 2018. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $750,000.00 in funding.
- The number of recipients for this funding is limited to 12 candidate(s).
- Eligible applicants include: Public and State controlled institutions of higher education, Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, Others (see text field entitled Additional Information on Eligibility for clarification).
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Shared Instrumentation for Animal Research (SIFAR) Grant Program (PAR-18-599) FAQs
What is the SIFAR Grant Program (PAR-18-599)?
The Shared Instrumentation for Animal Research (SIFAR) Grant Program (PAR-18-599) is an NIH funding opportunity that helps groups of NIH-funded investigators obtain advanced instrumentation needed to conduct animal-based experiments across NIH-supported biomedical research areas. A central requirement is shared access: the instruments are intended to be jointly used by multiple NIH-funded investigators rather than purchased for a single lab.
What is the main purpose of this funding opportunity?
The purpose is to support shared, advanced instrumentation that expands or accelerates NIH-funded animal research by enabling capabilities that multiple investigators need for their active projects involving animals (or closely related animal-derived materials).
Is this grant meant to fund equipment for a single lab?
No. The program is built around shared use. Applications are expected to describe a shared resource that will be used jointly by multiple NIH-funded investigators whose projects require similar animal research capabilities.
Does SIFAR fund new purchases, upgrades, or both?
It supports both the purchase of new equipment and upgrades of existing equipment, as long as the requested instruments are necessary to carry out research using animals or closely related animal-derived materials.
Does SIFAR fund a single instrument, or does it require multiple instruments?
SIFAR supports clusters of instruments rather than single standalone purchases. The application is expected to propose either (1) a specialized, integrated system made up of multiple commercially available components or (2) a coordinated set of instruments that together enable a focused, well-defined thematic area of animal research.
What does NIH mean by a "cluster of instruments" in this FOA?
Based on the opportunity description, a cluster is a grouped set of instruments that function together as an integrated system or as a coordinated suite supporting a specific animal research theme. The strength of an application depends on clearly explaining why the instruments must be assembled or configured as a group and how the combined configuration adds capability beyond what is already available.
Does NIH have a preference for certain types of instrument clusters?
NIH indicates a preference for uniquely configured systems, especially when the configuration enables innovative approaches or potentially transformative investigations. Applications are strongest when they justify the grouped configuration and show how it meaningfully expands shared capabilities for NIH-funded users.
What types of animal research does this program support?
The FOA is broad and supports animal-based experiments across the full range of NIH-supported biomedical research. It is broad with respect to both species and research domains, provided the request aligns with active NIH-funded research needs and the instruments will be operated as a shared resource.
What species are eligible under this opportunity?
The opportunity supports state-of-the-art commercially available technologies used in research with any vertebrate or invertebrate animal species.
What kinds of technologies or use-cases are considered responsive?
The description indicates it can include instrumentation that improves measurement, monitoring, imaging, phenotyping, behavioral assessment, or other specialized animal research workflows, as long as the need is tied to NIH-funded projects and the instruments will be shared.
Are the instruments required to be commercially available?
Yes. The program description emphasizes state-of-the-art commercially available technologies and notes clusters made up of multiple commercially available components.
What are the minimum cost requirements for instruments in the cluster?
There are two key rules based on the description provided: (1) at least one item within the proposed instrumentation cluster must cost at least $50,000 after all applicable discounts, and (2) no instrument included in the cluster may cost less than $20,000 after all applicable discounts.
Why is there a minimum price of $20,000 per instrument?
The description explains that this rule prevents applicants from bundling numerous small accessories or low-cost items to create an artificial cluster. Each instrument in the cluster must meet the minimum threshold after discounts.
Is there a maximum cost for a single instrument?
The provided information states there is no stated maximum price for an individual instrument. However, the overall award ceiling still applies to the total request.
What is the maximum total award amount?
The overall award ceiling is $750,000.
What funding mechanism is used for this program?
The announcement notes that this is an S10 mechanism.
Are clinical trials allowed under this FOA?
No. Clinical trials are not allowed under this funding opportunity.
Who is eligible to apply?
Eligibility is oriented toward research-performing organizations that can manage shared instrumentation and support multiple NIH-funded users. Eligible applicants include public and state-controlled institutions of higher education, private institutions of higher education, and nonprofit organizations (both 501(c)(3) and non-501(c)(3)) other than institutions of higher education, along with other applicants as described in the FOA's additional eligibility information.
Which federal agency sponsors this opportunity?
The sponsoring agency is the U.S. Department of Health and Human Services (HHS), National Institutes of Health (NIH).
What is the CFDA number and category listed for this opportunity?
The activity falls under the health category and is associated with CFDA 93.351.
How many awards were expected for the referenced cycle?
For the cycle reflected in the provided data, the opportunity listed an expected 12 awards.
What was the original closing date listed in the provided information?
The original closing date referenced in the provided data was May 31, 2018.
What makes an application especially competitive based on the description?
Applications are positioned to be strongest when they (1) clearly explain why the instruments must be assembled or configured as a group, (2) describe how the combined system improves capability beyond what is already available, and (3) show how the shared resource will accelerate or expand the science of the participating NIH-funded users. The description also notes a preference for uniquely configured systems that enable innovative or potentially transformative investigations.
Is the program limited to a particular biomedical research area?
No. The description characterizes the FOA as broad across NIH-supported biomedical research domains, so long as the request is tied to animal-based research needs of NIH-funded investigators and the instruments will be run as a shared resource.
Does the FOA require the instruments to support animal research specifically?
Yes. The instruments must be necessary to carry out research using animals or closely related animal-derived materials, and the thematic focus should be a well-defined area of animal research.
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